Protein function: Necessary for cellular interactions with laminin and the extracellular matrix. [The UniProt Consortium]

CMG-2, also known as anthrax toxin receptor 2 (ANTXR2) is a 45kD type I membrane protein with a von Willebrand factor A/integrin-like inserted domain in its extracellular region. CMG-2 binds laminin and collagen type IV. It also interacts with the protective antigen (PA) subunit of anthrax toxin. Applications:...

Capillary Morphogenesis Gene-2 (CMG-2) is a widely expressed anthrax toxin receptor (ATR) family protein (1-4). CMG-2 is a ~55 kD protein that contains a 31 amino acid (aa) signal sequence, a 287 aa extracellular domain (ECD), a 21 aa transmembrane sequence, and a 148 aa cytoplasmic domain. Unlike human CMG-2 which...

Capillary Morphogenesis Gene-2 (CMG-2) is a widely expressed anthrax toxin receptor (ATR) family protein (1-4). CMG-2 is a ~55 kD protein that contains a 31 amino acid (aa) signal sequence, a 287 aa extracellular domain (ECD), a 21 aa transmembrane sequence, and a 148 aa cytoplasmic domain. Unlike human CMG-2 which...

Source: Sf9 Insect cells.Sterile Filtered colorless solution.Anthrax toxin receptor 2, also known as ANTXR2, takes part in the configuration of little blood vessels (capillaries). ANTXR2 helps the toxin that leads to anthrax to attach to cells and trigger illness. ANTXR2 is necessary for cellular interactions with...